Amir Behdad, MD, MBA (he/him/his)
Professor and Regional Chair of Pathology
Cleveland Clinic Florida
Weston, Florida, United States
Phillip Michaels, MD (he/him/his)
Hematopathologist and molecular genetic pathologist
Brigham and Women's Hospital, Harvard Medical School
Boston, Massachusetts, United States
Description: This session will delve into the complexities of optimizing molecular testing and reporting, with a focus on balancing the expectations of oncologists and the practical realities faced by laboratories. Key topics include: Turnaround Time: Strategies for meeting oncologist demands for timely results while managing the logistical constraints of laboratory workflows. Minimum Gene List: Discussion on how to determine the essential genes for testing, ensuring both comprehensive results and efficient use of resources. Variant Allele Frequency (VAF): A review of how low VAFs should be reported for clinical relevance, considering sensitivity and specificity requirements, as well as practical considerations for detection limits. Integrated Reporting: Best practices for generating integrated molecular reports that combine genetic findings in the diagnosis. Attendees will gain a better understanding of how to meet the evolving needs of oncologists while ensuring molecular testing is accurate, efficient, and feasible within the laboratory setting..
If this session topic is of interest to you, please consider looking at the following course on AMP EDucation (AMPED™ Online)
Title: TP53 Mutations in Myeloid Neoplasms: From Clonal Hematopoiesis to Acute Leukemia
Click here to learn more.
Breakout Speaker: Annette S. Kim, MD, PhD (she/her/hers) – University of Michigan
Breakout Speaker: Marlise R. Luskin, MD MSCE (she/her/hers) – Dana-Farber Cancer Institute