Case Studies in Hematopathology

Co-Moderator (T & E Cmte)(s)

• 

  Richard Wong, MD, PhD

  Assistant Professor
  University of California San Diego
  La Jolla, California, United States
• 

  Kevin Fisher, MD, PhD

  Associate Professor
  Baylor College of Medicine
  Bellaire, Texas, United States

Session

Description: Challenging Case Studies are presented by trainees or technologists. They will discuss the case's clinical history, molecular analysis, interesting features, and the proposed diagnosis. Other molecular testing methods, if applicable, will be included in the presentation, including biopsies, gross/microscopic pathology, immunohistochemistry/flow cytometry, and cytogenetic findings.

Session

Objectives:
- Describe the context of a challenging clinical case.
- Discuss the molecular pathology techniques used in the diagnosis of the case.
- Propose a final diagnosis based upon findings and diagnostic evidence.

Presentations:

• 7:00 AM - 7:15 AM EST

  Resolving Amplicon Originated T-cell Receptor Clonotypes Using Anchor Multiplexed PCR
  

  Case Presenter: Mon Miyakawa-Liu, MD (they/them/theirs) – Stanford Health Care
• 7:15 AM - 7:30 AM EST

  Optical Genome Mapping Uncovers Disease-Defining Variants in an Adult T-lymphoblastic Leukemia and Impacts Prognosis
  

  Case Presenter: Amanda Maxfield – Geisel School of Medicine at Dartmouth
• 7:30 AM - 7:45 AM EST

  Interstitial Deletions of 11q: Rare class of non-canonical KMT2A fusion?
  

  Case Presenter: Jonathan H. Young, MD, PhD – Mass General Brigham
• 7:45 AM - 8:00 AM EST

  Beyond the Classics: The Spectrum of NPM1 Mutations
  

  Case Presenter: Ling-Lin Pai, MD PhD (she/her/hers) – Hospital of the University of Pennsylvania