AMP Guideline Essentials: DPYD Genotyping Recommendations

Description: Wondering which DPYD alleles are important to test and why? This condensed presentation of recent recommendations to aid in the design and validation of clinical DPYD genotyping assays from the AMP Clinical Practice Committee’s Pharmacogenomics (PGx) Working Group can help! Intended to promote standardization of testing across different laboratories and improve patient care, this guideline was collaboratively developed with the American College of Medical Genetics and Genomics (ACMG), Clinical Pharmacogenetics Implementation Consortium (CPIC), College of American Pathologists (CAP), Dutch Pharmacogenetics Working Group (DPWG) of the Royal Dutch Pharmacists Association, European Society for Pharmacogenomics and Personalized Therapy (ESPT), Pharmacogenomics Knowledgebase (PharmGKB®), and Pharmacogene Variation Consortium (PharmVar).