Integrating Absolute Copy Number Analysis into the Clinical NGS Workflow: Estimating Purity, Ploidy, and Cancer Cell Fraction

Learning Objectives:

• Upon completion, participate will be able to describe key pre-analytical factors and how they can affect the downstream molecular diagnostic process.
• Upon completion, participants will be able to describe the computational methods used to determine tumor content and estimate DNA yield from digital whole slide images.
• Upon completion, participants will be able to define the infrastructure and compute requirements and validation process for these methods to be integrated into the clinical workflow .